Web Analytics Made Easy - StatCounter
Direct Activation of BAX by BTSA1 Overcomes Apoptosis Resistance

Direct Activation of BAX by BTSA1 Overcomes Apoptosis Resistance

<

Figure thumbnail fx1

Download high-res image (998KB) ...

Download high-res image (1MB) ...

Download high-res image (848KB) ...

Download high-res image (906KB) ...

Download high-res image (2MB) ...

Download high-res image (1MB) ...

Figure 1: Direct BTSA1-mediated BAX activation induces apoptosis. BTSA1 binds the trigger

New Molecule Kills Resistant Cancer Cells in Acute Myeloid Leukemia

Novel treatment causes cancer to self-destruct without affecting healthy cells

Download high-res image (3MB) ...

EY Kho, Ph.D.

intrinsic.gif (481×367)

Abstract Image

Figure 5: BAX and BAK can be autoactivated by DNA damage independently of activators BID

Direct Activation of BAX by BTSA1 Overcomes Apoptosis Resistance in Acute Myeloid Leukemia | OtoRhinoLaryngology | Pinterest | Medicine

Figure 1: NOXA directly activates BAX and BAK independently of BID, BIM and PUMA

Figure 4: DNA damage activates BAX- and BAK-dependent mitochondrial apoptosis in transformed

Direct Activation of BAX by BTSA1 Overcomes Apoptosis Resistance in Acute Myeloid Leukemia | OtoRhinoLaryngology | Pinterest | Medicine

Direct Activation of BAX by BTSA1 Overcomes Apoptosis Resistance in Acute Myeloid Leukemia | OtoRhinoLaryngology | Pinterest | Medicine

Direct Activation of BAX by BTSA1 Overcomes Apoptosis Resistance in Acute Myeloid Leukemia | OtoRhinoLaryngology | Pinterest | Medicine

Direct Activation of BAX by BTSA1 Overcomes Apoptosis Resistance in Acute Myeloid Leukemia | OtoRhinoLaryngology | Pinterest | Medicine

[Blood Adv] Full Article | Graphical Abstract

Nexinhibs do not induce apoptosis or cell death. A and B,

Cancer Discovery: 7 (12)

Cancer-battling Einsteins sing "executioner's" song - Innovate Long Island

The apoptosis webinar provides an overview of the different modes of apoptosis and how to measure and detect apoptosis with the help of antibodies and kits.

Enlarge Cover

Reconstitution of Bax/Bak-null MEFs or mitochondria with wild

Figure 3: Quadruple deficiency of Bid, Bim, Puma and Noxa abrogates apoptosis in

Small-molecule PU.1 inhibitors decrease cell growth and increase apoptosis

Direct binding of 9 to Mcl-1 measured by fluorescence quenching.

Figure 1: Regulation of cytosolic BAX by autoihibited dimers. Cytosolic BAX can adopt a

Direct Activation of BAX by BTSA1 Overcomes Apoptosis Resistance in Acute Myeloid Leukemia | OtoRhinoLaryngology | Pinterest | Medicine

PU.1 knockdown decreases cell growth and clonogenicity and increases apoptosis of

Figure 1: BCL-xL is a direct target of miR-377. a

Figure-1-Apoptosis-The-intrinsic-apoptosis-pathway-can-

ZOOM IN

The Doctor's Tablet

Apoptosis regulator antibody to detect human Apoptosis regulator Validated on up to 12 cell lysates for western blotting.

Figure 1: Apoptotic pathways. Two major pathways lead to apoptosis: the intrinsic cell

Clotting Cascade

Marriage May Help Stave Off Dementia

New Imaging Study Reveals How Saturated Fatty Acids Damage Cells

¿Qué generan problemas en la apoptosis?

Modificaciones de las caspasas

Direct Activation of BAX by BTSA1 Overcomes Apoptosis Resistance in Acute Myeloid Leukemia | OtoRhinoLaryngology | Pinterest | Medicine

Figure 2: ABT-199-resistance is associated with the upregulation of Mcl-

0 replies 12 retweets 10 likes

Death Receptor Pathway

Cell Membrane Function Foldable

No Cell Phone Use Sign for Biology Class

8,402 curtidas, 63 comentários - Medical Doctors Worldwide (@medical.doctors) no

1 reply 6 retweets 12 likes

Cambios morfológicos fundamentales durante el proceso de necrosis

ZOOM IN

Fig. 3

0 replies 1 retweet 2 likes

By providing training on and access to naloxone, overdoes prevention and treatment programs have enabled

Direct Activation of BAX by BTSA1 Overcomes Apoptosis Resistance in Acute Myeloid Leukemia | Inmunología | Pinterest | Medicine

Graduate Programs in the Biomedical Sciences

0 replies 0 retweets 0 likes

This system is a very effective defense mechanism against cancer, since genetic defects occur early in the cancerous process. Apoptosis is the natural or ...

Figure 2: BCL-xL and miR-377 co-regulation mediates ABT-

Nucleotide-excision repair

Caspase 3 (active)- Western blot analysis of Jurkat cell lysates, from cells

Novel Treatment Causes Cancer to Self-Destruct Without Affecting Healthy Cells | Markets Insider

Fig. 6

Apoptosis.png (466×579)

What's the Word: Apophenia; News Items: Europa Venting, Piezoelectric Roads, Unhackable

Necrosis vs. Apoptosis

Novel Treatment Causes Cancer to Self-Destruct Without Affecting Healthy Cells

Proud of our collaborative work on RAF kinase pathway in cancer! http://dx.doi.org/10.1038/nrc.2017.79 … ...

Graphical representation of clonal evolution from the primary tumour to relapse

MAP kinase module

1 reply 15 retweets 9 likes

This animation shows natural-killer-cell-induced apoptosis of a virus-infected

Novel Treatment Causes Cancer to Self-Destruct Without Affecting Healthy Cells | Albert Einstein College of Medicine

... apoptosis by Annexin V staining. For the phospho-Erk analyses, cells were fixed in 2% paraformaldehyde/phosphate-buffered saline, stained with ...

'Multiple Sclerosis is a Tough Disease to Manage but It is Not Impossible'

0 replies 1 retweet 2 likes

(20) Auclair D, Miller D, Yatsula V, Pickett W, Carter C, Chang Y et al. Antitumor activity of sorafenib in FLT3-driven leukemic cells.

ZOOM IN

What is autophagia? / ¿Qué es la autofagia?

image_preview (400×391)

ZOOM IN

Fig. 8

Fig. 12

(1) Beeram M, Patnaik A, Rowinsky EK. Regulation of c-Raf-1: therapeutic implications. Clin Adv Hematol Oncol 2003; 1: 476-481.

4 replies 100 retweets 112 likes

[FIGURE 6 OMITTED]

Death Receptor Pathway

Apoptosis involves activation of the “executioner protein” BAX, which is very good at punching lethal holes in mitochondria, the organelles that generate a ...

0 replies 0 retweets 3 likes

Novel Treatment Causes Cancer to Self-Destruct Without Affecting Healthy Cells | United States News

Cover image Cancer Cell

Cáncer cervicouterino, por virus del papiloma humano